How to answer the beloved interview question, "Tell me about yourself"?

In an interview, "Tell me about yourself" might seem like an easy question, which you can answer randomly, but it's a question you must answer strategically. 

Instead of repeating what's in your resume (they already know it), take this as an opportunity to make things crystal clear and tell them about your strengths, how you are a perfect fit for that job, how ambitious/ passionate you are, and why they must hire you. 

You can start with some catchy words and explain them in your way, i.e., "I am a passionate and ambitious driven person; I thrive on challenges and constantly set my goals, so I don't get comfortable and settle down for less. I keep looking for opportunities ties to improve my skills."